yeah, when it thinks you're cheating it's because Wine only emulates the user application space of Windows, it doesn't emulate the kernel driver interface - and a lot of games load a kernel driver into the system behind your back so they can snoop around and check what other programs are running, checksum their own libraries, snoop the keyboard+mouse directly and compare them to the commands being given to the game, etc etc. It's a common but rather annoying method that also is the reason a lot of games don't work on Win64.